Holyoak, Todd : rechercher sur Z-Library

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1

Gluconeogenic Enzymes in β-Cells: Pharmacological Targets for Improving Insulin Secretion

Westermeier, Francisco, Holyoak, Todd, Asenjo, Joel L., Gatica, Rodrigo, Nualart, Francisco, Burbulis, Ian, Bertinat, Romina

Journal:

Trends in Endocrinology & Metabolism

Année:

2019

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2019

2

The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery

Aron W. Fenton, Troy A. Johnson, Todd Holyoak

Journal:

Protein Science

Année:

2010

Langue:

english

Fichier:

PDF, 174 KB

english, 2010

3

Strategies for folding of affinity tagged proteins using GroEL and osmolytes

Hiroo Katayama, Mitchell McGill, Andrew Kearns, Marek Brzozowski, Nicholas Degner, Bliss Harnett, Boris Kornilayev, Dubravka Matković-Čalogović, Todd Holyoak, James P. Calvet, Edward P. Gogol, John Se

Journal:

Journal of Structural and Functional Genomics

Année:

2009

Langue:

english

Fichier:

PDF, 554 KB

english, 2009

4

Determination of the structure of the MinD–ATP complex reveals the orientation of MinD on the membrane and the relative location of the binding sites for MinE and MinC

Wei Wu, Kyung-Tae Park, Todd Holyoak, Joe Lutkenhaus

Journal:

Molecular Microbiology

Année:

2011

Langue:

english

Fichier:

PDF, 919 KB

english, 2011

5

Differentiating a Ligand's Chemical Requirements for Allosteric Interactions from Those for Protein Binding. Phenylalanine Inhibition of Pyruvate Kinase†,‡

Williams, Rachel, Holyoak, Todd, McDonald, Gissel, Gui, Chunshan, Fenton, Aron W.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 293 KB

english, 2006

6

Structures of Rat Cytosolic PEPCK: Insight into the Mechanism of Phosphorylation and Decarboxylation of Oxaloacetic Acid†,‡

Sullivan, Sarah M., Holyoak, Todd

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 648 KB

english, 2007

7

The Min Oscillator Uses MinD-Dependent Conformational Changes in MinE to Spatially Regulate Cytokinesis

Kyung-Tae Park, Wei Wu, Kevin P. Battaile, Scott Lovell, Todd Holyoak, Joe Lutkenhaus

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2011

8

Active-Site Gating Regulates Substrate Selectivity in a Chymotrypsin-Like Serine Protease: The Structure of Haemophilus influenzae Immunoglobulin A1 Protease

Troy A. Johnson, Jiazhou Qiu, Andrew G. Plaut, Todd Holyoak

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.79 MB

english, 2009

9

The Ω-Loop Lid Domain of Phosphoenolpyruvate Carboxykinase Is Essential for Catalytic Function

Johnson, Troy A., Holyoak, Todd

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.67 MB

english, 2012

10

Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith–Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity

Adams, David R., Yuan, Hongjie, Holyoak, Todd, Arajs, Katrina H., Hakimi, Parvin, Markello, Thomas C., Wolfe, Lynne A., Vilboux, Thierry, Burton, Barbara K., Fajardo, Karin Fuentes, Grahame, George, H

Journal:

Molecular Genetics and Metabolism

Année:

2014

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2014

11

Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase

Fenton, Aron, Holyoak, Todd, Zhang, Bing, Deng, Junpeng, Tang, Qingling, Prasannan, Charulata B.

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 39 KB

english, 2013

12

Structural Investigation of the Binding of Nucleotide to Phosphoenolpyruvate Carboxykinase by NMR †

Holyoak, Todd, Nowak, Thomas

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 136 KB

english, 2001

13

Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition ‡

Stiffin, Rose Mary, Sullivan, Sarah M., Carlson, Gerald M., Holyoak, Todd

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 604 KB

english, 2008

14

Increasing the Conformational Entropy of the Ω-Loop Lid Domain in Phosphoenolpyruvate Carboxykinase Impairs Catalysis and Decreases Catalytic Fidelity,

Johnson, Troy A., Holyoak, Todd

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 4.49 MB

english, 2010

15

pH Dependence of the Reaction Catalyzed by Avian Mitochondrial Phosphoenolpyruvate Carboxykinase †

Holyoak, Todd, Nowak, Thomas

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 169 KB

english, 2004

16

Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase

Holyoak, Todd, Zhang, Bing, Deng, Junpeng, Tang, Qingling, Prasannan, Charulata B., Fenton, Aron W.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 3.04 MB

english, 2013

17

2.4 Å Resolution Crystal Structure of the Prototypical Hormone-Processing Protease Kex2 in Complex with an Ala-Lys-Arg Boronic Acid Inhibitor †,‡

Holyoak, Todd, Wilson, Mark A., Fenn, Timothy D., Kettner, Charles A., Petsko, Gregory A., Fuller, Robert S., Ringe, Dagmar

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 583 KB

english, 2003

18

Structural Basis for Differences in Substrate Selectivity in Kex2 and Furin Protein Convertases †,‡

Holyoak, Todd, Kettner, Charles A., Petsko, Gregory A., Fuller, Robert S., Ringe, Dagmar

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2004

19

Structural Insights into the Mechanism of PEPCK Catalysis †,‡

Holyoak, Todd, Sullivan, Sarah M., Nowak, Thomas

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 910 KB

english, 2006

20

Effect of a Y265F Mutant on the Transamination-Based Cycloserine Inactivation of Alanine Racemase †,‡

Fenn, Timothy D., Holyoak, Todd, Stamper, Geoffrey F., Ringe, Dagmar

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 788 KB

english, 2005

21

Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid

Balan, Marc D., Mcleod, Matthew J., Lotosky, William R., Ghaly, Mark, Holyoak, Todd

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.77 MB

english, 2015

22

Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase

Johnson, Troy A., Mcleod, Matthew J., Holyoak, Todd

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 5.63 MB

english, 2016

23

Asymmetric Anchoring Is Required for Efficient Ω-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase

Cui, Danica S., Broom, Aron, Mcleod, Matthew J., Meiering, Elizabeth M., Holyoak, Todd

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2017

24

Exploring the limits of the usefulness of mutagenesis in studies of allosteric mechanisms

Tang, Qingling, Alontaga, Aileen Y., Holyoak, Todd, Fenton, Aron W.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2017

25

Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella

Eckhard, Ulrich, Bandukwala, Hina, Mansfield, Michael J., Marino, Giada, Cheng, Jiujun, Wallace, Iain, Holyoak, Todd, Charles, Trevor C., Austin, John, Overall, Christopher M., Doxey, Andrew C.

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2017

26

A Putative Alzheimer's Disease Risk Allele in PCK1 Influences Brain Atrophy in Multiple Sclerosis

Xia, Zongqi, Chibnik, Lori B., Glanz, Bonnie I., Liguori, Maria, Shulman, Joshua M., Tran, Dong, Khoury, Samia J., Chitnis, Tanuja, Holyoak, Todd, Weiner, Howard L., Guttmann, Charles R. G., De Jager,

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 269 KB

english, 2010

27

Cytosolic phosphoenolpyruvate carboxykinase is expressed in α‐cells from human and murine pancreas

Westermeier, Francisco, Holyoak, Todd, Gatica, Rodrigo, Martínez, Fernando, Negrón, Marianne, Yáñez, Alejandro J., Nahmias, Daniel, Nualart, Francisco, Burbulis, Ian, Bertinat, Romina

Journal:

Journal of Cellular Physiology

Année:

2019

Langue:

english

Fichier:

PDF, 4.98 MB

english, 2019

28

3-((carboxymethyl)thio)-picolinic acid – A novel inhibitor of phosphoenolpyruvate carboxykinase

Mcleod, Matthew J, Krismanich, Anthony P, Assoud, Abdeljalil, Dmitrienko, Gary Igor, Holyoak, Todd

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2019